The word meticulous was first used in a mid-sixteenth century collection of poetry. It was borrowed from the Latin word meticulosus, which literally meant "frightful" or "timid". This is because of a connection between being attentive to detail and being scared of imperfections - think obsessive compulsive disorder. The root of meticulosus is the fourth declension noun metus, or "fear"; any further beyond that and linguists have no clue. If you know Spanish, metus should be familiar as the root of miedo, and the Latin word was actually used in English with a meaning of "fear" until it died out in the seventeenth century. According to Google NGrams, usage of meticulous in literature over time peaked in the year 1985 and has been declining since, although it seems like Google searches for it have increased since when the website first started measuring it in 2004.
Hello! I'm Adam Aleksic. This year, I graduated from Harvard University with a degree in Government and Linguistics. There, I co-founded the Harvard Undergraduate Linguistics Society and wrote a thesis on Serbo-Croatian language policy, magna cum laude. In addition to etymology, I also really enjoy philosophy, trivia, vexillology, geography, board games, conlanging, art history, and law.