The word muscle came to us in the late fourteenth century from the Middle French word muscle, with basically the same meaning (there were some weird alterations along the way, like muskylle and muscule, but history has canceled those out). This too was borrowed in the fourteenth century, albeit from Latin. In this case, the word in question was musculus, which too meant muscle... figuratively. It carried quite a different literal meaning, that of "little mouse"! The connection occurred because muscles really do sort of look like tiny murine lumps under your skin. Musculus is a diminutive of mus, the normal word for mouse. Through Proto-Italic mus, this is reconstructed as having derived from the Proto-Indo-European word muhs, still meaning "mouse". Curiously, correlations between mice and muscles can also be found in languages from Arabic to Greek to German, as well.
Adam Aleksic, a leading contender for valedictorian of his high school, is a 211-month-old boy with disturbing interests in etymology, vexillology, geography, and law. Adam would like to one day visit Tajikistan and probably isn't spying for the Kyrgyz government.
The Etymology Nerd