The word patsy as meaning "someone who is blamed for a crime" originated in US slang in the 1870s, and there are a lot of different theories about the etymology of that term. It's a possibility is that it could be from the Italian word pazzo, which meant "madman", but that's pretty loosely supported. One hint is that the earliest spellings of patsy were with a capital first letter, which implies that it's a name. It might come from the Irish diminutive of Patrick, Paddy, which was considered a stereotypical immigrant name at the time. It could also come from Patsy Bolivar, a character in vaudevillian skits who was always blamed by the other schoolboys for classroom pranks (the actors' traveling could have helped it spread around the country). The word really only got popularized in the early 1900s, eventually peaking in usage in the 1970s.
Hello! I'm Adam Aleksic. This year, I graduated from Harvard University with a degree in Government and Linguistics. There, I co-founded the Harvard Undergraduate Linguistics Society and wrote a thesis on Serbo-Croatian language policy, magna cum laude. In addition to etymology, I also really enjoy philosophy, trivia, vexillology, geography, board games, conlanging, art history, and law.